Despoina Dimakou

Project: Thesis: Colorectal cancer liver metastasis│Role of liver immune cells

• Deep understanding of animal experimentation licenses in accordance with GCP and 3R ethics principles
• Health monitoring of mice and reporting of symptoms in iRATS animal database and scoresheets
• Establishing murine liver cells isolation and culture protocol

Project: Solid tumors│DNA-binding proteins as therapeutic targets

• Autonomously designed and performed experiments able to determine protein structures
• Collected and analyzed research data to create representative graphs highlighting results for presentations
• Worked both independently and collaboratively in fast-paced laboratory environment

Project: Solid tumors│Protein purification and functional characterization

• Collaborated with other researchers to develop successful functional biochemical assays to determine protein function
• Recorded experimental data in electronic laboratory notebook to statistically analyze and interpret experimental findings
• Provided project progress updates in weekly meetings and troubleshot experimental pitfalls in protein purification process

Project: Alcohol-related liver fibrosis│Biomarkers profile of individuals at risk to develop personalized healthcare strategies

• Worked in interdisciplinary team to develop a biomarkers' prognostic panel of liver fibrosis
• Collaborated with physicians for collection of liver biopsies
• Processed clinical data and patients' informed consent forms