Summary
Overview
Work History
Education
Skills
Personal Information
Languages
Accomplishments
Certification
Affiliations
References
Timeline
Generic

Marina Castiello

Basel

Summary

Highly motivated, results-driven professional with a proven track record of working effectively both independently and within teams. Skilled in scientific/technical writing, presenting complex information and managing multiple projects with precision in fast-paced environments. Known for proactive problem-solving and creative, solution-oriented thinking, I bring strong organizational skills and meticulous attention to detail. Demonstrated success in meeting tight deadlines, contributing innovative ideas, and consistently delivering high-quality, accurate data and reports to achieve team goals.

Overview

14
14
years of professional experience
1
1
Certification

Work History

Expert Science and Technology (Senior Scientist)

Novartis Pharma GDD–TRD–BPD–DSP
Basel
04.2020 - Current
  • Scientific Experiment Design & Knowledge Transfer: Lead design and planning of scientific experiments to support biologic drug development at Novartis, collaborating across multifunctional teams to ensure knowledge transfer and delivery.
  • Technical Lab Management: Oversee lab activities, transferring procedures to team members, pilot plants and production sites, including troubleshooting and process optimization.
  • Data Analysis & Reporting: Interpret data, generate scientific documents and deliver precise development reports and transfer protocols; actively present findings to project leaders and teams.
  • Team Leadership & Mentorship: Coach and guide junior staff in experiment execution, fostering skill development and encouraging team growth.
  • Lean Lab Bronze Certification (Feb 2024): Achieved certification as a Lean Lab facilitator, leading meetings and applying Lean methodologies to streamline processes and drive continuous improvement within the DSP team.
  • User Representation & Advocacy (2023-Present): Serve as DSP User Representative, ensuring DSP user needs are addressed in lab and office relocation to Novartis Campus, advocating for a user-focused environment.

Scientist

Novartis Pharma GDD–TRD–BPD–DS
Basel
04.2018 - 03.2020
  • Data Documentation & Analysis: Documented and interpreted experimental data, provided insights for future experiment design and ensured precise data reporting.
  • Technical Proficiency: Skilled in chromatography, ultrafiltration and TECAN robotic systems; contributed to instrument maintenance and lab infrastructure.
  • Innovation & Knowledge Sharing: Proposed new ideas, delivered presentations to lab leads and trained technicians and external partners to strengthen team capabilities.
  • IQP Bronze Certified: Demonstrated quality process knowledge with IQP Bronze certification.

Associate Scientist

Novartis Pharma GDD–BPD–DS
Basel
06.2017 - 03.2018
  • Drug Substance/Process Development: Conducted experiments for timely delivery of drug substances and products, including process validation studies with comprehensive reporting.
  • Data Management & Method Optimization: Documented and interpreted raw data, optimizing existing methods for improved efficiency.
  • Lab Maintenance & Inventory Management: Scheduled equipment maintenance, maintained lab infrastructure, and managed chemical and material inventory.
  • Collaboration & SOP Contribution: Partnered with associates to ensure smooth project deliveries; contributed to lab procedures, repo and SOPs.
  • Technical Proficiency: Skilled in BioELN and Biologics Sample Management (BSM) systems.

Downstream Development Research Laboratory Scientist

Menarini Biotech
Pomezia
10.2015 - 06.2017
  • Downstream Process Development: Led design, optimization, and scale-up of downstream purification processes for GMP biopharmaceuticals, focusing on monoclonal antibodies and recombinant proteins.
  • Technology Transfer: Facilitated technology transfer of downstream processes to internal manufacturing teams, ensuring alignment with required specifications.
  • Advanced Technical Skills: Proficient in column chromatography, ultrafiltration and viral clearance studies, executing processes from bench to pilot scale.
  • Process Validation & Robustness Testing: Designed and executed validation studies, testing processes under various conditions to ensure process robustness and compliance with cGMP standards.

Viral Clearance Study

Texcell – North America, Inc
Frederick
09.2016 - 10.2016
  • Regulatory Compliance: Conducted viral clearance testing for investigational new drug submission for Menarini monoclonal antibodies, meeting regulatory authority requirements.
  • Process Development: Executed critical viral clearance steps, including low pH treatment and virus removal filtration, ensuring process safety and compliance.

Manufacturing Science & Technology Primary (MS&T I) – Process Science Intern

Novartis Vaccines & Diagnostics (a GlaxoSmithKline company)
Sovicille
03.2015 - 09.2015
  • Downstream Process Development: Led design and optimization of purification processes for monoclonal antibodies and recombinant proteins in GMP biopharmaceuticals.
  • Technology Transfer: Executed successful technology transfer to manufacturing teams, ensuring compliance with required specifications.
  • Laboratory Expertise: Conducted bench and pilot-scale chromatography, ultrafiltration, diafiltration and viral clearance studies, demonstrating proficiency in multiple purification techniques.
  • Experimental Design & Validation: Designed and executed experiments, including validation studies, to assess process robustness in accordance with cGMP standards.

Traineeship

European Commission – Joint Research Centre (JRC)
Ispra
10.2013 - 10.2014
  • Research Focus: Developed methods for detecting and characterizing nanomaterials, with an emphasis on in vitro testing of nanoparticle-protein interactions and potential toxicity.
  • Experimental Support: Provided scientific support using specialized instruments, including UV-Vis Spectroscopy and Fluorescence for protein-ligand interactions and CD and DLS for biochemical characterization.
  • Data Analysis & Reporting: Contributed to data analysis and preparation of scientific reports on nanoparticle toxicity evaluations.

Laboratory Practice in the Pharmaceutical and Toxicological Chemistry Department

University of Naples “Federico II”
Naples
10.2011 - 07.2012
  • Organic Compound Synthesis: Conducted synthesis and purification of organic compounds using various organic chemistry reactions.
  • Chromatography Expertise: Proficient in chromatography techniques, including TLC and column chromatography for compound separation.
  • Research & Analysis: Performed bibliographic research using SciFinder Scholar and PubMed; utilized CS-ChemDraw for molecular editing.
  • Instrumentation Knowledge: Familiar with MS, NMR, HPLC, GC-MS and SDS-PAGE for compound characterization and analysis.

Professional training in pharmacy

Farmacia “Faretra Pavone Dr.ssa Rosina”
Avellino
11.2010 - 03.2011
  • Medication Management: Ensured accurate checking and storage of medicines.
  • Public Dispensing: Dispensed medications to the public, providing guidance and support. My focus on clear communication and attentiveness allowed me to address their needs effectively, enhancing their overall experience and fostering trust in the pharmacy services provided.

Education

Qualification to practice the profession of pharmacist -

University of Naples “Federico II”
12.2012

Master’s Degree - Pharmaceutical Chemistry and Technology

University of Naples “Federico II”
Italy
07.2012

Italian High School Diploma -

Liceo Classico “P.Colletta”
Avellino
07.2007

Skills

  • Project Management
  • Experimental design
  • Drug Inventory Management
  • Safety processes and procedures
  • Attention to Detail
  • Friendly and positive Attitude
  • Troubleshooting
  • Analytical Thinking
  • Multitasking Abilities
  • Visual storytelling
  • Innovation and Creativity
  • Strong organizational skills

Personal Information

  • Date of Birth: 07/07/89
  • Nationality: Italian
  • Driving License: type B

Languages

Italian
First Language
English
Proficient (C2)
C2
German
Elementary (A2)
A2

Accomplishments

  • TRD Culture Award (2023): Honored with the TRD Culture Award at Novartis for outstanding performance and significant contributions in in-vivo CAR therapy, demonstrating passion and dedication.
  • Galaxy Awards: Received various Galaxy Awards at Novartis for successfully managing multiple projects throughout the years.
  • Awakened Curiosity Badge: Recognized for my commitment to continuous learning and innovation, reflecting my enthusiasm for problem-solving and driving innovative solutions.

Certification

  • Lean Lab Bronze Certification (2024): Successfully led the attainment of this certification, showcasing dedication to operational excellence and involvement in cross-functional roles, including managing supplier relationships, process documentation and overseeing finance audits for compliance and efficiency.
  • 200-Hour Vinyasa Yoga Certification (2021): this training has been instrumental in developing my mental and physical resilience, equipping me to tackle new challenges with determination and confidence.
  • Conscious Collaboration and Impact (2020): Developed skills in effective teamwork and collaboration, enhancing overall project outcomes.
  • Proactive Self-Leadership (2020): Focused on personal accountability and leadership in various professional contexts.
  • The Role of Emotional Intelligence and Communication (2020): Gained insights into leveraging emotional intelligence for improved communication and relationships in the workplace.
  • IQP Bronze Certification (2018): Achieved through demonstrating quality process knowledge and commitment to improving operational standards.
  • IELTS (International English Language Testing System) (2013): Intensive course preparation at Kaplan International College London, Russell Square (London, UK) with overall band score of 7.0.
  • ECDL (European Computer Driving Licence): Demonstrated proficiency in computer skills and competencies.

Affiliations

  • I enjoy expressing my creativity through painting and drawing with pastels and pencils. I also have a keen interest in arts, attending fairs and museums, and I love sharing my paintings with friends or publishing them on social media.
  • I have a passion for exploring new cultures and my meaningful travel experiences, such as studying abroad and living in a foreign country, have enhanced my adaptability and ability to improvise in unexpected situations.
  • I enjoy practicing Functional Training, yoga, acroyoga, gymnastics and acrobatics which sparked my interest in understanding the human body to enhance strength, balance and agility. Through Vinyasa Yoga, I have learned to deepen and embody these qualities, enabling me to navigate obstacles gracefully while also supporting and uplifting others on their journeys.

References

References available upon request.

Timeline

Expert Science and Technology (Senior Scientist)

Novartis Pharma GDD–TRD–BPD–DSP
04.2020 - Current

Scientist

Novartis Pharma GDD–TRD–BPD–DS
04.2018 - 03.2020

Associate Scientist

Novartis Pharma GDD–BPD–DS
06.2017 - 03.2018

Viral Clearance Study

Texcell – North America, Inc
09.2016 - 10.2016

Downstream Development Research Laboratory Scientist

Menarini Biotech
10.2015 - 06.2017

Manufacturing Science & Technology Primary (MS&T I) – Process Science Intern

Novartis Vaccines & Diagnostics (a GlaxoSmithKline company)
03.2015 - 09.2015

Traineeship

European Commission – Joint Research Centre (JRC)
10.2013 - 10.2014

Laboratory Practice in the Pharmaceutical and Toxicological Chemistry Department

University of Naples “Federico II”
10.2011 - 07.2012

Professional training in pharmacy

Farmacia “Faretra Pavone Dr.ssa Rosina”
11.2010 - 03.2011
  • Lean Lab Bronze Certification (2024): Successfully led the attainment of this certification, showcasing dedication to operational excellence and involvement in cross-functional roles, including managing supplier relationships, process documentation and overseeing finance audits for compliance and efficiency.
  • 200-Hour Vinyasa Yoga Certification (2021): this training has been instrumental in developing my mental and physical resilience, equipping me to tackle new challenges with determination and confidence.
  • Conscious Collaboration and Impact (2020): Developed skills in effective teamwork and collaboration, enhancing overall project outcomes.
  • Proactive Self-Leadership (2020): Focused on personal accountability and leadership in various professional contexts.
  • The Role of Emotional Intelligence and Communication (2020): Gained insights into leveraging emotional intelligence for improved communication and relationships in the workplace.
  • IQP Bronze Certification (2018): Achieved through demonstrating quality process knowledge and commitment to improving operational standards.
  • IELTS (International English Language Testing System) (2013): Intensive course preparation at Kaplan International College London, Russell Square (London, UK) with overall band score of 7.0.
  • ECDL (European Computer Driving Licence): Demonstrated proficiency in computer skills and competencies.

Qualification to practice the profession of pharmacist -

University of Naples “Federico II”

Master’s Degree - Pharmaceutical Chemistry and Technology

University of Naples “Federico II”

Italian High School Diploma -

Liceo Classico “P.Colletta”
Marina Castiello